Cromosoma 21 (2022)

Nick experiences writer's block as part of a really bad day. When he falls asleep, he dreams of writing a great song but can't remember it once he wakes up, so Joe and Kevin try to re-create Nick's bad day to so that he will be able to dream his great song again.

Joe questions his relationship with Stella when invited to a fashion event. Meanwhile, Macy accepts a date with Randolph and decides to make him into a "Nick clone".

The members of JONAS try their hand at acting in a school production of the Three Musketeers. Joe then becomes jealous after finding out that Van Dyke Tosh, who fills in for Joe due to stage fright, is Stella's love interest.

A magazine linked Joe in a relationship with a celebrity named Fiona Skye (Sara Paxton). When Fiona begins to follow Joe, he and his brothers realize that something must be done.

A teacher lets Joe slide on an accident with a fire alarm, but gives his friend Abby detention for the same mistake. Joe then attempts to get detention which he succeeds, and tries to apologize to Abby with Nick and Kevin's help. Meanwhile, Stella struggles with her grade in P.E. class, and tries to make sewing a sport.

Stella becomes jealous of Macy spending time with Joe not knowing they're actually planning a surprise party for her.

Kevin, Joe and Nick are left home alone for a week and they try to behave and impress their parents, but when Frankie throws a party, their plans go into a tailspin. Meanwhile, Stella unwittingly "takes control" of the JONAS fan club from Macy.

When Joe, Nick, and Kevin forget Stella's birthday, they try to plan her another one but schedule it at the same time as a "big interview".

When Kevin thinks there is a ghost in the firehouse, he enlists Stella, Joe and Nick to help him find it. They do not think there is a ghost until Nick disappears.

Van Dyke asks Stella on a date to El Meat, a new, all-meat restaurant, and a jealous Joe crashes the date with Macy, in order to keep an eye on Stella. Kevin has an addiction to Nick's cookies and Nick tries to teach Kevin about self-control.

Kevin's old girlfriend, Anya has joined their school, but the kids in the school make fun of her because they find her eccentric. Meanwhile, Joe, Nick, Stella and Macy try to find out who has been taking picture of Jonas and uploading it on Macy's website

The boys will be the judges of a beauty contest. Stella decides to be part of the contest.

As the JONAS World Concert Tour draws closer, Joe and Stella come to terms with being apart from one another over the summer. Meanwhile, Kevin and Joe devise a plan to help Nick ace his geometry test after their dad threatens not to send the brothers on tour unless they pass all of their school exams